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Cycloastragenol Good Supplier In Bulk Supply High Purity 84605-18-5 We supply high quality Cycloastragenol (CAS 84605-18-5), in stock, factory directly supply to clients, lower prices, more competitiveness.
Cycloastragenol is Colorless needle crystal, while it's Molecular Formula is C30H50O5. Cycloastragenol is an aglycone derivative of astragaloside IV found in the root of Korean Astragalus membranaceus.
The CAS number of Cycloastragenol is 84605-18-5.
More information of Cycloastragenol 84605-18-5 are:
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Synonyms |
1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene,9,19-cyclolanostane-3,6,16,25-tetrol deriv.;Cyclogalagenin;Astramembrangenin;Cyclogalegigenin;9,19-Cyclolanostane-3,6,16,25-tetrol, 20,24-epoxy-,(3beta,6alpha,16beta,24R)-; |
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CAS Number |
84605-18-5 |
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Molecular Formula |
C30H50O5 |
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Molecular Weight |
490.724 |
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Density |
1.2 g/cm3 |
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Boiling Point |
617.2 °C at 760 mmHg |
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Flash Point |
327.1 °C |
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HS CODE |
2942000000 |
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PSA |
90.15000 |
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LogP |
4.43660 |
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Pka |
14.57±0.29(Predicted) |
Cycloastragenol (TA-65), a small-triterpenoid purified from the root of an Asian medicinal herb, has currently received particular attention for its potential to regulate transcription of telomerase. TA-65 is capable to increase average telomere length and to decrease the percentage of critically short telomeres and DNA damage in MEFs that harbor critically short telomeres. The effects on telomerase appear to be in common with other triterpenoid saponins (ie, ginsenosides RG1 and Rg3). These compounds at concentrations from 1 to 20 μM were reported to protect against IL-1β-, H2O2-, and tert-butylhydroperoxide-induced senescence in human chondrocytes, endothelial progenitor cells and fibroblasts, respectively.
InChI:InChI=1/C30H50O5/c1-24(2)20(33)8-11-30-16-29(30)13-12-26(5)23(28(7)10-9-21(35-28)25(3,4)34)18(32)15-27(26,6)19(29)14-17(31)22(24)30/h17-23,31-34H,8-16H2,1-7H3/t17-,18-,19-,20-,21+,22?,23?,26+,27-,28-,29?,30?/m0/s1
Articles related to Cycloastragenol:
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Article |
Source |
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Structure of cyclochivinoside C from Astragalus chivensis |
Naubeev,Uteniyazov , p. 560 - 562 (2007) |
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The use of two-phase acid hydrolysis method of preparing ring [...] (by machine translation) |
- Paragraph 0024-0066, (2019/07/08) |
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