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Cost-effective and customizable BAM-15 210302-17-3 factory We supply high quality N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine (CAS 210302-17-3), in stock, factory directly supply to clients, lower prices, more competitiveness.
N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine is , while it's Molecular Formula is C16H10F2N6O. BAM 15, is a mitochondrial protonophore uncoupler that does not depolarize the plasma membrane and protects mice from acute renal ischemic-reperfusion injury.
The CAS number of N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine is 210302-17-3.
More information of N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine 210302-17-3 are:
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CAS Number |
210302-17-3 |
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Molecular Formula |
C16H10F2N6O |
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Molecular Weight |
340.292 |
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Density |
1.548±0.06 g/cm3(Predicted) |
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Boiling Point |
421.7±55.0 °C(Predicted) |
BAM15 (210302-17-3) is a mitochondrial protonophore uncoupler with fewer off-target effects (EC50 = 270 nM in L6 myoblast mitochondria.)1,2 Compared to FCCP, an uncoupler of equal potency, BAM15 stimulates a higher maximum rate of mitochondrial respiration and does not depolarize the plasma membrane.2 Stimulates energy expenditure, protects against obesity and improves glycemic control in rodent models.3 Reverses diet-induced obesity and insulin resistance in mice.4 Attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.5
Articles related to N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine:
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Article |
Source |
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Chemistry of furazano[3,4-b]pyrazines 3. Method for the synthesis of 5,6-disubstituted furazano[3,4-b]pyrazines |
Starchenkov,Andrianov , p. 1219 - 1233 (2007/10/03) |
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