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General Description |
Creatine ethyl ester hydrochloride is a synthetic form of the organic compound creatine, which is found naturally in the body and is also commonly used as a dietary supplement by athletes and bodybuilders. This particular form of creatine is bound to an ethyl ester group, which is thought to improve its absorption and bioavailability in the body compared to other forms of creatine. The addition of the hydrochloride component to creatine ethyl ester is believed to further enhance its solubility and stability. As a result, creatine ethyl ester hydrochloride is often promoted for its potential to increase muscle mass, enhance athletic performance, and improve exercise endurance. However, there is limited scientific evidence to support these claims, and the safety and long-term effects of this compound are still under investigation. |
InChI:InChI=1/C6H13N3O2.ClH/c1-3-11-5(10)4-9(2)6(7)8;/h3-4H2,1-2H3,(H3,7,8);1H
The invention provides a novel synthetic...
The present invention provides a creatin...
The creatine transporter deficiency is a...
Membrane permeable prodrugs of creatine ...
ethanol
Creatinine
ethyl 2-(3-methylguanidino)acetate hydrochloride
ethyl acetate
| Conditions | Yield |
|---|---|
|
ethanol;
With
acetyl chloride;
at 35 - 60 ℃;
Creatinine;
at 35 - 50 ℃;
for 2 - 8h;
|
80% |
|
ethanol;
With
acetyl chloride;
Creatinine;
at 37 ℃;
for 10 - 20h;
Product distribution / selectivity;
|
37% |
ethanol
Creatinine
ethyl 2-(3-methylguanidino)acetate hydrochloride
| Conditions | Yield |
|---|---|
|
With
phosgene; dmap;
at 10 ℃;
for 0.5h;
Reagent/catalyst;
Sealed tube;
|
89% |
|
With
chlorophosphonic acid;
at 0 - 60 ℃;
for 0.75h;
|
73% |
|
at 37 ℃;
for 20h;
Product distribution / selectivity;
Acidic conditions;
|
54% |
|
With
hydrogenchloride;
|
|
|
With
acetyl chloride;
In
water;
at 40 ℃;
|
|
|
With
hydrogenchloride;
|
ethanol
Creatinine
creatinine
creatinine
